For those of us who have trouble keeping all this stuff in memory, I've made a page showing the main characters in Macross Frontier, with pics of the character and of their VAs, along with info about each VA. Click here or on the picture to go to the full page.
There is basically just a lot of good voice-acting in this show. Nakamura Yuuichi shows that it is no accident he has become such a hot property. And Nakajima Megumi is making the most of her debut role as Lanka, despite the odd bit of newbie flatness. I also thought her insert song in ep3 was excellent.
But Endou Aya as Sheryl is really blowing me away. Once again, it's no accident that she has three starring roles this spring (in this, Neo-Angelique, and My-Otome s.ifr).
Add names like Kamiya Hiroshi (Zetsubou Sensei), Fukuyama Jun (Lerouch), Kuwashima Houko (Shuurei in Saiunkoku), Kobayashi Sanae (Maya in Glass Mask, one of the greatest performances I've ever seen), Konishi Katsuyuki (Kamina in Gurren-Laggan), and Sugita Tomokazu (Kyon), and you've really got a cast that can do the job.